Article
The craniofacial phenotype of the Crouzon mouse: analysis of a model for syndromic craniosynostosis using three-dimensional MicroCT.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Nov 2006
Perlyn Chad A, DeLeon Valerie B, Babbs Christian, Govier Daniel, Burell Lance, Darvann Tron, Kreiborg Sven, Morriss-Kay Gillian
Abstract excerpt
OBJECTIVE: To characterize the craniofacial phenotype of a mouse model for Crouzon syndrome by a quantitative analysis of skull morphology in mutant and wild-type mice and to compare the findings with skull features observed in humans with Crouzon syndrome. METHODS: MicroCT scans and skeletal preparations were obtained on previously described Fgfr2(C342Y/+) Crouzon mutant mice and wild-type mice at 6 weeks of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.