Contributing Factors for Angle's Class III Phenotype in Crouzon Syndrome.

doi:10.23804/ejpd.2025.2207

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Article

Contributing Factors for Angle's Class III Phenotype in Crouzon Syndrome.

European journal of paediatric dentistry - 4 Mar 2026

Protzenko M, Viana de Araújo C A, de Carvalho Gonzalez S M, Rolemberg Riba F, Protzenko T, Llerena Junior J

Abstract excerpt

AIM: Crouzon syndrome (CS) is a rare genetic condition characterised by craniofacial malformations due to mutations in the FGFR2 gene. This study aimed to evaluate the contributing factors for Angle's Class III malocclusion in patients with CS through cephalometric analysis. Six patients with confirmed CS diagnosis were included in the study. Cephalometric measurements were performed using CT scans and compared...

Topics

Humans
Craniofacial Dysostosis
Malocclusion, Angle Class III
Phenotype
Cephalometry
Male
Female
Child
Receptor, Fibroblast Growth Factor, Type 2
Adolescent
Tomography, X-Ray Computed
Mutation

Source

Open in PubMed

Identifiers

PMID: 41055378
DOI: 10.23804/ejpd.2025.2207

Genes

CS
FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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