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Article

Computational mouse atlases and their application to automatic assessment of craniofacial dysmorphology caused by the Crouzon mutation Fgfr2(C342Y).

Journal of anatomy - 1 Jul 2007

Olafsdóttir Hildur, Darvann Tron A, Hermann Nuno V, Oubel Estanislao, Ersbøll Bjarne K, Frangi Alejandro F, Larsen Per, Perlyn Chad A, Morriss-Kay Gillian M, Kreiborg Sven

Abstract excerpt

Crouzon syndrome is characterized by premature fusion of sutures and synchondroses. Recently, the first mouse model of the syndrome was generated, having the mutation Cys342Tyr in Fgfr2c, equivalent to the most common human Crouzon/Pfeiffer syndrome mutation. In this study, a set of micro-computed tomography (CT) scannings of the skulls of wild-type mice and Crouzon mice were analysed with respect to the...

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Identifiers

PMID: 17553099
DOI: 10.1111/j.1469-7580.2007.00751.x
PMCID: PMC2375796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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