Article
[Immunohistochemistry using clone VE1 is an economic, specific and sensitive method for detecting the presence of BRAFV600E mutations in melanoma].
Annales de dermatologie et de venereologie - 1 Mar 2018
Etienne M, Oca F, Prunier-Mirebeau D, Croué A, Martin L
Abstract excerpt
BACKGROUND: Determination of BRAF mutation status is mandatory in the management of patients with inoperable stage IIIC or stage IV melanoma. Currently, molecular biology (MB) has been validated for detecting the presence of BRAF mutations. OBJECTIVE: To compare the sensitivity, specificity and cost of immunohistochemistry (IHC) (clone VE1) versus BM methods (qPCR and Sanger sequencing). PATIENTS AND METHODS: All...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
