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Article

Is immunohistochemistry of BRAF V600E useful as a screening tool and during progression disease of melanoma patients?

BMC cancer - 18 Nov 2016

Schirosi Laura, Strippoli Sabino, Gaudio Francesca, Graziano Giusi, Popescu Ondina, Guida Michele, Simone Giovanni, Mangia Anita

Abstract excerpt

BACKGROUND: In clinical practice the gold standard method to assess BRAF status in patients with metastatic melanoma is based on molecular assays. Recently, a mutation-specific monoclonal antibody (VE1), which detects the BRAF V600E mutated protein, has been developed. With this study we aimed to confirm the clinical value of the VE1 Ventana® antibody, as today a univocal validated and accredited...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27863476
DOI: 10.1186/s12885-016-2951-4
PMCID: PMC5116153

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Is immunohistochemistry of BRAF V600E useful as a screening tool and during progression disease of melanoma patients?PMID 27863476Read ↗

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