Article
Polymorphisms in the NLRP3 gene and risk of primary gouty arthritis.
Molecular medicine reports - 1 Jun 2013
Meng Dong-Mei, Zhou Yu-Jiao, Wang Luan, Ren Wei, Cui Ling-Ling, Han Lin, Qu Zheng-Hai, Li Chang-Gui, Zhao Jia-Jun
Abstract excerpt
The aim of the present study was to investigate the association between genetic variants in 17 tagSNPs of the NLRP3 gene and the susceptibility to primary gouty arthritis. A genotype-phenotype analysis of 480 primary gout and 480 control patients was performed. Samples from all the patients were collected from The Affiliated Hospital of Medical College (Qingdao, China). Seventeen tagSNPs of the NLRP3 gene were...
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