Article
rs3806268 of NLRP3 gene polymorphism is associated with the development of primary gout.
International journal of clinical and experimental pathology - 1 Jan 2015
Deng Jianping, Lin Wen, Chen Yunpeng, Wang Xin, Yin Zhong, Yao Chunhong, Liu Tangbing, Lv Yonghong
Abstract excerpt
The aim of the present study was to investigate the association between seven functional SNPs in NALP3 gene and the susceptibility to primary gout. A total of 247 patients with primary gout and 247 controls were selected in this study. Genotyping of NALP3 rs4612666, rs3806268, rs12239046, rs10754558, rs7512998, and was performed using the Sequenom MassARRAY platform. Comparison analysis...