Article
Association of complement receptor 1 gene polymorphisms with cognitive function.
Physiological genomics - 1 Feb 2018
Zijlstra L E, Jukema J W, Mooijaart S P, de Vries M A, Stott D J, Castro Cabezas M, Trompet S
Abstract excerpt
Previous evidence suggest involvement of the complement receptor 1 (CR1) in development of Alzheimer's disease. We investigated the association of CR1 gene polymorphisms with cognitive function in older subjects. Single nucleotide polymorphisms (SNPs) within the CR1 region on chromosome 1 ( n = 73) were assessed in 5,244 participants in the PROspective Study of Pravastatin in the Elderly at Risk (51.9% female,...
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