Article
Complement receptor 1 gene polymorphisms are associated with cardiovascular risk.
Atherosclerosis - 1 Feb 2017
de Vries Marijke A, Trompet Stella, Mooijaart Simon P, Smit Roelof A J, Böhringer Stefan, Castro Cabezas Manuel, Jukema J Wouter
Abstract excerpt
BACKGROUND AND AIMS: Inflammation plays a key role in atherosclerosis. The complement system is involved in atherogenesis, and the complement receptor 1 (CR1) plays a role facilitating the clearance of immune complexes from the circulation. Limited evidence suggests that CR1 may be involved in cardiovascular disease. We investigated the relationship between CR1 gene polymorphisms and cardiovascular risk. METHODS:...
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