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Article

Iron-related gene variants and brain iron in multiple sclerosis and healthy individuals.

NeuroImage. Clinical - 1 Jan 2018

Hagemeier Jesper, Ramanathan Murali, Schweser Ferdinand, Dwyer Michael G, Lin Fuchun, Bergsland Niels, Weinstock-Guttman Bianca, Zivadinov Robert

Abstract excerpt

Brain iron homeostasis is known to be disturbed in multiple sclerosis (MS), yet little is known about the association of common gene variants linked to iron regulation and pathological tissue changes in the brain. In this study, we investigated the association of genetic determinants linked to iron regulation with deep gray matter (GM) magnetic susceptibility in both healthy controls (HC) and MS patients. Four...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29201641
DOI: 10.1016/j.nicl.2017.11.003
PMCID: PMC5699896

Genes

HFE

Variants

rs1800562
rs1800562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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