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Brain structure in healthy adults is related to serum transferrin and the H63D polymorphism in the <i>HFE</i> gene

9 Jan 2012

Abstract excerpt

Control of iron homeostasis is essential for healthy central nervous system function: iron deficiency is associated with cognitive impairment, yet iron overload is thought to promote neurodegenerative diseases. Specific genetic markers have been previously identified that influence levels of transferrin, the protein that transports iron throughout the body, in the blood and brain. Here, we discovered that...

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PMID: 22232660
DOI: 10.1073/pnas.1105543109

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