Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease.

Journal of neurochemistry - 1 Jun 2010

Johnstone Daniel, Milward Elizabeth A

Abstract excerpt

Iron is essential in the brain, yet too much iron can be toxic. Tight regulation of iron in the brain may involve intrinsic mechanisms that control internal homeostasis independent of systemic iron status. Iron abnormalities occur in various neurological disorders, usually with symptoms or neurop...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Brain Diseases
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemochromatosis Protein

Share to Histocompatibility Antigens Class I

Share to Membrane Proteins

Share to Molecular Biology

Source

Identifiers

PMID: 20345752
DOI: 10.1111/j.1471-4159.2010.06697.x

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20345752-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetic approaches to understanding the roles and regulation of iron in brain health and disease.PMID 20345752Read ↗

The roles of iron and HFE genotype in neurological diseases.Semantic proximity Read ↗

Brain Iron Metabolism and Neurodegenerative DisordersSemantic proximity Read ↗

HFE gene variants, iron, and lipids: a novel connection in Alzheimerâ€™s diseaseSemantic proximity Read ↗

Hemochromatosis neural archetype reveals iron disruption in motor circuits.Semantic proximity Read ↗

Neurodegeneration with brain iron accumulation.Semantic proximity Read ↗

Hereditary Causes of Disturbed Iron Homeostasis in the Central Nervous SystemSemantic proximity Read ↗

Neurodegeneration with Brain Iron Accumulation: Genetic Diversity and Pathophysiological Mechanisms.Semantic proximity Read ↗

Neurodegenerations with Brain Iron Accumulation.Semantic proximity Read ↗

Whole-exome sequencing identifies protein-coding variants associated with brain iron in 29,828 individuals.Semantic proximity Read ↗

Hemochromatosis Neural Archetype Reveals Iron Disruption in Motor CircuitsSemantic proximity Read ↗

Iron dysregulation and neurodegeneration: the molecular connection.Semantic proximity Read ↗

Genetics of neurodegeneration with brain iron accumulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.