Article
Adult Primary Immune Thrombocytopenia: Spleen Histology Findings and Outcomes According to Rituximab Use Based on Analysis of 41 Cases.
The American journal of surgical pathology - 1 Mar 2018
Furudoï Adeline, Rivière Étienne, Lazaro Estibaliz, Furudoï Enio, Viallard Jean-François, Parrens Marie
Abstract excerpt
Immune thrombocytopenia (ITP) is an acquired antibody-mediated disease, for which splenectomy remains a curative treatment. We analyzed histology and phenotypes of ITP-splenectomy specimens from 41 adult patients, with different previous ITP-specific treatments, including B-cell-depleting rituximab (RTX) or not, in an attempt to predict splenectomy success or failure on the basis of day 56 postoperative platelet...
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