Article
T cell receptor VB repertoire diversity in patients with immune thrombocytopenia following splenectomy.
Clinical and experimental immunology - 1 Sept 2003
Fogarty P F, Rick M E, Zeng W, Risitano A M, Dunbar C E, Bussel J B
Abstract excerpt
In recent years, a pathophysiological role for T cells in immune thrombocytopenia (ITP) has been established. We applied cDNA size distribution analysis of the T cell receptor (TCR) beta-variable (VB) complementarity-determining region 3 (CDR3) in order to investigate T cell repertoire diversity...
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