Article
A distinct plasmablast and naïve B-cell phenotype in primary immune thrombocytopenia.
Haematologica - 1 Jun 2016
Flint Shaun M, Gibson Adele, Lucas Geoff, Nandigam Raghava, Taylor Louise, Provan Drew, Newland Adrian C, Savage Caroline O, Henderson Robert B
Abstract excerpt
Primary immune thrombocytopenia is an autoimmune disorder in which platelet destruction is a consequence of both B- and T-cell dysregulation. Flow cytometry was used to further characterize the B- and T-cell compartments in a cross-sectional cohort of 26 immune thrombocytopenia patients including antiplatelet antibody positive (n=14) and negative (n=12) patients exposed to a range of therapies, and a cohort of...
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