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Article

Prognostic utility of six mutated genes for older patients with acute myeloid leukemia.

International journal of cancer - 15 Apr 2018

Wang Jinghan, Ma Zhixin, Wang Qinrong, Guo Qi, Huang Jiansong, Yu Wenjuan, Wang Huanping, Huang Jingwen, Washington Shao Yang, Chen Suning, Jin Jie

Abstract excerpt

Approximately 50% of older patients with acute myeloid leukemia (AML) do not obtain chromosomal abnormalities as an effective risk-stratification, and present cytogenetically normal AML (CN-AML). To develop a reliable prediction model for stratifying the risk of these elderly patients, we conducted a study with a discovery and validation design. As a result, we found the top 6 mutated genes in the discovery...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Leukemic

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Source

Identifiers

PMID: 29193057
DOI: 10.1002/ijc.31178

Genes

DNMT3A
FLT3
IDH1
NPM1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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