Article
Cooperative Control of Ecdysone Biosynthesis in Drosophila by Transcription Factors Séance, Ouija Board, and Molting Defective.
Genetics - 1 Feb 2018
Uryu Outa, Ou Qiuxiang, Komura-Kawa Tatsuya, Kamiyama Takumi, Iga Masatoshi, Syrzycka Monika, Hirota Keiko, Kataoka Hiroshi, Honda Barry M, King-Jones Kirst, Niwa Ryusuke
Abstract excerpt
Ecdysteroids are steroid hormones that control many aspects of development and physiology. During larval development, ecdysone is synthesized in an endocrine organ called the prothoracic gland through a series of ecdysteroidogenic enzymes encoded by the Halloween genes. The expression of the Halloween genes is highly restricted and dynamic, indicating that their spatiotemporal regulation is mediated by their...
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