Article
Cis-regulation in the Drosophila Bithorax Complex.
Advances in experimental medicine and biology - 1 Jan 2010
Maeda Robert K, Karch François
Abstract excerpt
The discovery of the first homeotic mutation by Calvin Bridges in 1915 profoundly influenced the way we think about developmental processes. Although many mutations modify or deform morphological structures, homeotic mutations cause a spectacular phenotype in which a morphological structure develops like a copy of a structure that is normally found elsewhere on an organism's body plan. This is best illustrated in...
Topics
- Animals
- Body Patterning
- Chromatin
- Chromosomes
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Homeodomain Proteins
- Larva
- MicroRNAs