Article
The Drosophila Zinc Finger Transcription Factor Ouija Board Controls Ecdysteroid Biosynthesis through Specific Regulation of spookier.
PLoS genetics - 1 Dec 2015
Komura-Kawa Tatsuya, Hirota Keiko, Shimada-Niwa Yuko, Yamauchi Rieko, Shimell MaryJane, Shinoda Tetsuro, Fukamizu Akiyoshi, O'Connor Michael B, Niwa Ryusuke
Abstract excerpt
Steroid hormones are crucial for many biological events in multicellular organisms. In insects, the principal steroid hormones are ecdysteroids, which play essential roles in regulating molting and metamorphosis. During larval and pupal development, ecdysteroids are synthesized in the prothoracic gland (PG) from dietary cholesterol via a series of hydroxylation and oxidation steps. The expression of all but one...
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