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Article

Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera.

Developmental biology - 15 Oct 2006

Ono Hajime, Rewitz Kim F, Shinoda Tetsuro, Itoyama Kyo, Petryk Anna, Rybczynski Robert, Jarcho Michael, Warren James T, Marqués Guillermo, Shimell Mary Jane, Gilbert Lawrence I, O'Connor Michael B

Abstract excerpt

Ecdysteroids regulate many key developmental events in arthropods including molting and metamorphosis. Recently, members of the Drosophila Halloween group of genes, that are required for embryonic viability and cuticle deposition, have been shown to code for several cytochrome P450 enzymes that catalyze the terminal hydroxylation steps in the conversion of cholesterol to the molting hormone 20-hydroxyecdysone....

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PMID: 16949568
DOI: 10.1016/j.ydbio.2006.07.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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