Article

Opportunistic binding of EcR to open chromatin drives tissue-specific developmental responses

2022-05-10

Abstract excerpt

Steroid hormones perform diverse biological functions in developing and adult animals. However, the mechanistic basis for their tissue specificity remains unclear. In Drosophila , the ecdysone steroid hormone is essential for coordinating developmental timing across physically separated tissues. Ecdysone directly impacts genome function through its nuclear receptor, a heterodimer of the EcR and Usp proteins. Liga...

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Literature Corpus work: ee176adb-b882-5a5d-860f-64e4b9cfc6b0
DOI: 10.1101/2022.05.09.491237

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Opportunistic binding of EcR to open chromatin drives tissue-specific developmental responsesDOI 10.1101/2022.05.09.491237Read

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