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Article

Ste20-like kinase, SLK, a novel mediator of podocyte integrity.

American journal of physiology. Renal physiology - 1 Jul 2018

Cybulsky Andrey V, Papillon Joan, Guillemette Julie, Belkina Natalya, Patino-Lopez Genaro, Torban Elena

Abstract excerpt

SLK is essential for embryonic development and may play a key role in wound healing, tumor growth, and metastasis. Expression and activation of SLK are increased in kidney development and during recovery from ischemic acute kidney injury. Overexpression of SLK in glomerular epithelial cells/podocytes in vivo induces injury and proteinuria. Conversely, reduced SLK expression leads to abnormalities in cell...

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Source

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Identifiers

PMID: 29187370
DOI: 10.1152/ajprenal.00238.2017
PMCID: PMC6335006

Genes

SLK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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