Article

The Protective Role of KANK1 in Podocyte Injury

2024-04-25

Abstract excerpt

Approximately 30% of steroid-resistant nephrotic syndromes are attributed to monogenic disorders that involve 27 genes. Mutations in KANK family members have also been linked to nephrotic syndrome; however, the precise mechanism remains elusive. To investigate this, podocyte-specific Kank1 knockout mice were generated to examine phenotypic changes. In the initial assessment under normal conditions, Kank1 knockout...

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Literature Corpus work: b15c9555-21a0-56ac-93fb-d7ff4bb95105
DOI: 10.20944/preprints202404.1697.v1

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