Article
Out on a LIM: chronic kidney disease, podocyte phenotype and the Wilm's tumor interacting protein (WTIP).
Transactions of the American Clinical and Climatological Association - 1 Jan 2011
Sedor John R, Madhavan Sethu M, Kim Jane H, Konieczkowski Martha
Abstract excerpt
Normal function of the glomerular filtration barrier requires wild-type differentiation of the highly specialized glomerular epithelial cell, the podocyte. Podocytes express three distinct domains, consisting of a cell body, primary processes, and secondary foot processes (FP). These FP express slit diaphragms, which are highly specialized cell-cell contacts critical for filtration-barrier function. Foot...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.