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Article

An Msh3 ATPase domain mutation has no effect on MMR function.

BMC research notes - 25 Nov 2017

Edwards Yasmin

Abstract excerpt

OBJECTIVE: To demonstrate that the Msh3 ATPase domain is required for DNA mismatch repair and tumor suppression in a murine model. RESULTS: The DNA mismatch repair proteins are members of the ABC family of ATPases. ATP binding and hydrolysis regulates their mismatch repair function. In the current study, a mouse model was generated harboring a glycine to aspartic acid residue change in the Walker A motif of the...

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Identifiers

PMID: 29178930
DOI: 10.1186/s13104-017-2939-4
PMCID: PMC5702223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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