Article
Saccharomyces cerevisiae Msh2p and Msh6p ATPase activities are both required during mismatch repair.
Molecular and cellular biology - 1 Dec 1998
Studamire B, Quach T, Alani E
Abstract excerpt
In the Saccharomyces cerevisiae Msh2p-Msh6p complex, mutations that were predicted to disrupt ATP binding, ATP hydrolysis, or both activities in each subunit were created. Mutations in either subunit resulted in a mismatch repair defect, and overexpression of either mutant subunit in a wild-type...
Topics
- Adenosine Triphosphatases
- Amino Acid Sequence
- Base Pair Mismatch
- Binding, Competitive
- DNA Repair
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression
- Molecular Sequence Data
- MutS Homolog 2 Protein
- Mutation
- Oligodeoxyribonucleotides
- Phenotype
- Protein Binding
- Protein Conformation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Alignment