Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

3D aggregate culture improves metabolic maturation of human pluripotent stem cell derived cardiomyocytes

27 Nov 2017

Abstract excerpt

Abstract Three‐dimensional (3D) cultures of human pluripotent stem cell derived cardiomyocytes (hPSC‐CMs) hold great promise for drug discovery, providing a better approximation to the in vivo physiology over standard two‐dimensional (2D) monolayer cultures. However, the transition of CM differentiation protocols from 2D to 3D cultures is not straightforward. In this work, we relied on the aggregation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Pancreatic function and diabetes
Share to Pluripotent Stem Cells Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29178315
DOI: 10.1002/bit.26504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

3D aggregate culture improves metabolic maturation of human pluripotent stem cell derived cardiomyocytesPMID 29178315Read ↗

Metabolic Maturation in hiPSC-Derived Cardiomyocytes: Emerging Strategies for Inducing the Adult Cardiac PhenotypeSemantic proximity Read ↗

Lipid availability influences the metabolic maturation of human pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

A Multi-omics Method Enabled by Sequential Metabolomics and Proteomics for Human Pluripotent Stem Cell-derived CardiomyocytesSemantic proximity Read ↗

A roadmap for the characterization of energy metabolism in human cardiomyocytes derived from induced pluripotent stem cellsSemantic proximity Read ↗

PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

Multi-omic analysis reveals maturation programs in human pluripotent stem cell-derived cardiomyocytes during long-term cultureSemantic proximity Read ↗

Early multi-omic signatures and machine learning models predict cardiomyocyte differentiation efficiency and enable robust hPSC differentiation to cardiomyocytesSemantic proximity Read ↗

Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissuesSemantic proximity Read ↗

Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytesSemantic proximity Read ↗

Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspectsSemantic proximity Read ↗

Multiomics-based assessment of 2D and 3D human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathySemantic proximity Read ↗

Metabolically-Driven Maturation of hiPSC-Cell Derived Cardiac ChipSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.