Article
Differential early subcortical involvement in genetic FTD within the GENFI cohort.
NeuroImage. Clinical - 1 Jan 2021
Bocchetta Martina, Todd Emily G, Peakman Georgia, Cash David M, Convery Rhian S, Russell Lucy L, Thomas David L, Eugenio Iglesias Juan, van Swieten John C, Jiskoot Lize C, Seelaar Harro, Borroni Barbara, Galimberti Daniela, Sanchez-Valle Raquel, Laforce Robert, Moreno Fermin, Synofzik Matthis, Graff Caroline, Masellis Mario, Carmela Tartaglia Maria, Rowe James B, Vandenberghe Rik, Finger Elizabeth, Tagliavini Fabrizio, de Mendonça Alexandre, Santana Isabel, Butler Chris R, Ducharme Simon, Gerhard Alexander, Danek Adrian, Levin Johannes, Otto Markus, Sorbi Sandro, Le Ber Isabelle, Pasquier Florence, Rohrer Jonathan D
Abstract excerpt
BACKGROUND: Studies have previously shown evidence for presymptomatic cortical atrophy in genetic FTD. Whilst initial investigations have also identified early deep grey matter volume loss, little is known about the extent of subcortical involvement, particularly within subregions, and how this differs between genetic groups. METHODS: 480 mutation carriers from the Genetic FTD Initiative (GENFI) were included...
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