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Leukotriene B4 receptor 2 gene polymorphism (rs1950504, Asp196Gly) leads to enhanced cell motility under low-dose ligand stimulation.

Experimental & molecular medicine - 24 Nov 2017

Jang Jae-Hyun, Wei Jun-Dong, Kim Minsup, Kim Joo-Young, Cho Art E, Kim Jae-Hong

Abstract excerpt

Recently, single-nucleotide polymorphisms (SNPs) in G-protein-coupled receptors (GPCRs) have been suggested to contribute to physiopathology and therapeutic effects. Leukotriene B4 receptor 2 (BLT2), a member of the GPCR family, plays a critical role in the pathogenesis of several inflammatory diseases, including cancer and asthma. However, no studies on BLT2 SNP effects have been reported to date. In this study,...

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PMID: 29170475
DOI: 10.1038/emm.2017.192
PMCID: PMC5704194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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