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Article

Lipid-associated GWAS loci as important markers of the risk, severity, and clinical course of peripheral artery disease.

Expert review of molecular diagnostics - 1 Nov 2024

Zhabin Sergey N, Lazarenko Victor A, Azarova Iuliia E, Klyosova Elena Yu, Bykanova Marina A, Churnosov Mikhail I, Solodilova Maria A, Polonikov Alexey V

Abstract excerpt

BACKGROUND: This study investigated the relationship between lipid-associated loci identified through genome-wide association studies (GWAS) and the risk of peripheral artery disease (PAD), its severity, as well as clinical and laboratory features. RESEARCH DESIGN AND METHODS: A study included 1263 unrelated Russian subjects, consisting of 620 patients diagnosed with PAD and 643 healthy controls. Thirteen single...

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PMID: 39450831
DOI: 10.1080/14737159.2024.2421497

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