Article
A Novel Multiplex HRM Assay to Detect Clopidogrel Resistance.
Scientific reports - 22 Nov 2017
Zhang Lichen, Ma Xiaowei, You Guoling, Zhang Xiaoqing, Fu Qihua
Abstract excerpt
Clopidogrel is an antiplatelet medicine used to prevent blood clots in patients who have had a heart attack, stroke, or other symptoms. Variability in the clinical response to clopidogrel treatment has been attributed to genetic factors. In particular, five SNPs of rs4244285, rs4986893, rs12248560, rs662 and rs1045642 have been associated with resistance to clopidogrel therapy in Chinese population. This work...