Article
T85C polymorphisms of the dihydropyrimidine dehydrogenase gene detected in gastric cancer tissues by high-resolution melting curve analysis.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Jan 2012
Fang Weijia, Xu Nong, Jin Dazhi, Chen Yu, Chen Xiaogang, Zheng Yi, Shen Hong, Yuan Ying, Zheng Shusen
Abstract excerpt
BACKGROUND/AIMS: Dihydropyrimidine dehydrogenase is a key enzyme acting on the metabolic pathway of medications for gastric cancer. High-resolution melting curve technology, which was developed recently, can distinguish the wild-type dihydropyrimidine dehydrogenase gene from multiple polymorphisms by fluorescent quantitative polymerase chain reaction products in a direct and effective manner. MATERIALS AND...
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