Article
Immune-Based Therapies and the Role of Microsatellite Instability in Pancreatic Cancer.
Genes - 29 Dec 2020
Ghidini Michele, Lampis Andrea, Mirchev Milko B, Okuducu Ali Fuat, Ratti Margherita, Valeri Nicola, Hahne Jens C
Abstract excerpt
Pancreatic cancer is one of the most aggressive malignancies with limited treatment options thus resulting in high morbidity and mortality. Among all cancers, with a five-year survival rates of only 2-9%, pancreatic cancer holds the worst prognostic outcome for patients. To improve the overall survival, an earlier diagnosis and stratification of cancer patients for personalized treatment options are urgent needs....
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