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Article

The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels.

Neuron - 6 Dec 2017

Mazzoni Jenna, Smith Julian R, Shahriar Sanjid, Cutforth Tyler, Ceja Bernardo, Agalliu Dritan

Abstract excerpt

Coordinating angiogenesis with acquisition of tissue-specific properties in endothelial cells is essential for vascular function. In the retina, endothelial cells form a blood-retina barrier by virtue of tight junctions and low transcytosis. While the canonical Norrin/Fz4/Lrp5/6 pathway is essential for angiogenesis, vascular remodeling, and barrier maturation, how these diverse processes are coordinated remains...

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Identifiers

PMID: 29154126
DOI: 10.1016/j.neuron.2017.10.025
PMCID: PMC5728434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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