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Article

Talin-dependent integrin activation is required for endothelial proliferation and postnatal angiogenesis.

Angiogenesis - 1 Feb 2021

Pulous Fadi E, Carnevale Jamie C, Al-Yafeai Zaki, Pearson Brenna H, Hamilton Jamie A G, Henry Curtis J, Orr A Wayne, Petrich Brian G

Abstract excerpt

Integrin activation contributes to key blood cell functions including adhesion, proliferation and migration. An essential step in the cell signaling pathway that activates integrin requires the binding of talin to the β-integrin cytoplasmic tail. Whereas this pathway is understood in platelets in detail, considerably less is known regarding how integrin-mediated adhesion in endothelium contributes to postnatal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33113074
DOI: 10.1007/s10456-020-09756-4
PMCID: PMC8441968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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