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Article

Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature.

Science (New York, N.Y.) - 21 Nov 2008

Stenman Jan M, Rajagopal Jay, Carroll Thomas J, Ishibashi Makoto, McMahon Jill, McMahon Andrew P

Abstract excerpt

Every organ depends on blood vessels for oxygen and nutrients, but the vasculature associated with individual organs can be structurally and molecularly diverse. The central nervous system (CNS) vasculature consists of a tightly sealed endothelium that forms the blood-brain barrier, whereas blood vessels of other organs are more porous. Wnt7a and Wnt7b encode two Wnt ligands produced by the neuroepithelium of the...

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Identifiers

PMID: 19023080
DOI: 10.1126/science.1164594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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