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Article

Fzd7 (Frizzled-7) Expressed by Endothelial Cells Controls Blood Vessel Formation Through Wnt/β-Catenin Canonical Signaling.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2016

Peghaire Claire, Bats Marie Lise, Sewduth Raj, Jeanningros Sylvie, Jaspard Beatrice, Couffinhal Thierry, Duplàa Cécile, Dufourcq Pascale

Abstract excerpt

OBJECTIVE: Vessel formation requires precise orchestration of a series of morphometric and molecular events controlled by a multitude of angiogenic factors and morphogens. Wnt/frizzled signaling is required for proper vascular formation. In this study, we investigated the role of the Fzd7 (frizzled-7) receptor in retinal vascular development and its relationship with the Wnt/β-catenin canonical pathway and Notch...

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Identifiers

PMID: 27758766
DOI: 10.1161/ATVBAHA.116.307926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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