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Article

A 3' untranslated region polymorphism rs2304277 in the DNA repair pathway gene OGG1 is a novel risk modulator for urothelial bladder carcinoma.

Annals of human genetics - 1 Mar 2018

Ahmed Tayyaba, Nawaz Saira, Noreen Rabia, Bangash Kashif Sardar, Rauf Abdur, Younis Muhammad, Anwar Khursheed, Khawaja Muhammad Athar, Azam Maleeha, Qureshi Abid Ali, Akhter Saeed, Kiemeney Lambertus A, Qamar Raheel, Ali Syeda Hafiza Benish

Abstract excerpt

Altered DNA repair capacity may affect an individual's susceptibility to cancers due to compromised genomic integrity. This study was designed to elucidate the association of selected polymorphisms in DNA repair genes with urothelial bladder carcinoma (UBC). OGG1 rs1052133 and rs2304277, XRCC1 rs1799782 and rs25487, XRCC3 rs861539, XPC , and XPD were genotyped using polymerase chain...

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Share to 3' Untranslated Regions
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Share to Polymorphism, Restriction Fragment Length
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Source

Identifiers

PMID: 29139108
DOI: 10.1111/ahg.12225

Genes

OGG1
UBC
XPC
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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