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Article

NPM1 Mutation Analysis in Acute Myeloid Leukemia: Comparison of Three Techniques - Sanger Sequencing, Pyrosequencing, and Real-Time Polymerase Chain Reaction.

Turkish journal of haematology : official journal of Turkish Society of Haematology - 1 Mar 2018

Kumar Dushyant, Mehta Anurag, Panigrahi Manoj Kumar, Nath Sukanta, Saikia Kandarpa Kumar

Abstract excerpt

OBJECTIVE: Nucleophosmin-1 (NPM1) mutations have prognostic importance in acute myeloid leukemia (AML) patients with intermediate-risk karyotype at diagnosis. Approximately 30% of newly diagnosed cytogenetically normal AML (CN-AML) patients harbor the NPM1 mutation in India. In this study we compared the efficiency of three molecular techniques in detecting NPM1 mutation in peripheral blood and bone marrow...

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Topics

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Share to DNA Mutational Analysis
Share to Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nuclear Proteins

Share to Nucleophosmin

Share to Prognosis

Share to Real-Time Polymerase Chain Reaction

Share to Sensitivity and Specificity

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 29129825
DOI: 10.4274/tjh.2017.0095
PMCID: PMC5843774

Genes

NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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