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Article

Cis-SNPs Set Testing and PrediXcan Analysis for Gene Expression Data using Linear Mixed Models.

Scientific reports - 10 Nov 2017

Zeng Ping, Wang Ting, Huang Shuiping

Abstract excerpt

Understanding the functional mechanism of SNPs identified in GWAS on complex diseases is currently a challenging task. The studies of expression quantitative trait loci (eQTL) have shown that regulatory variants play a crucial role in the function of associated SNPs. Detecting significant genes (called eGenes) in eQTL studies and analyzing the effect sizes of cis-SNPs can offer important implications on the...

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Share to Databases, Nucleic Acid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 29127305
DOI: 10.1038/s41598-017-15055-8
PMCID: PMC5681585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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