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ABC Transporters in Cancer Stem Cells: Beyond Chemoresistance

8 Nov 2017

Abstract excerpt

The efficacy of chemotherapy is one of the main challenges in cancer treatment and one of the major obstacles to overcome in achieving lasting remission and a definitive cure in patients with cancer is the emergence of cancer resistance. Indeed, drug resistance is ultimately accountable for poor treatment outcomes and tumour relapse. There are various molecular mechanisms involved in multidrug resistance, such as...

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PMID: 29117122
DOI: 10.3390/ijms18112362

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