Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer Stem Cells as a Potential Target to Overcome Multidrug Resistance

2 Jun 2020

Abstract excerpt

Multidrug resistance (MDR), which is a significant impediment to the success of cancer chemotherapy, is attributable to various defensive mechanisms in cancer. Initially, overexpression of ATP-binding cassette (ABC) transporters such as P-glycoprotein (P-gp) was considered the most important mechanism for drug resistance; hence, many investigators for a long time focused on the development of specific ABC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Epigenetics and DNA Methylation
Share to Hedgehog Signaling Pathway Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32582535
DOI: 10.3389/fonc.2020.00764

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer Stem Cells as a Potential Target to Overcome Multidrug ResistancePMID 32582535Read ↗

At the crossroads of cancer stem cells and targeted therapy resistance.Semantic proximity Read ↗

Drug resistance mechanisms of cancer stem-like cells and their therapeutic potential as drug targetsSemantic proximity Read ↗

Ovarian cancer stem cell: A potential therapeutic target for overcoming multidrug resistanceSemantic proximity Read ↗

Cancer Stem Cells: A New Paradigm for Understanding Tumor Growth and Progression and Drug ResistanceSemantic proximity Read ↗

Drug resistance and Cancer stem cellsSemantic proximity Read ↗

A Brief Review on Chemoresistance; Targeting Cancer Stem Cells as an Alternative ApproachSemantic proximity Read ↗

Comprehensive review of drug resistance in mammalian cancer stem cells: implications for cancer therapySemantic proximity Read ↗

Understanding and targeting cancer stem cells: therapeutic implications and challengesSemantic proximity Read ↗

ABC Transporters in Cancer Stem Cells: Beyond ChemoresistanceSemantic proximity Read ↗

Multidrug Resistance and Cancer Stem Cells in Neuroblastoma and HepatoblastomaSemantic proximity Read ↗

Cancer Stem Cells (CSCs) as a Rational Therapeutic Cancer Target, and Screening for CSC-targeting Drugs.Semantic proximity Read ↗

Insights into new mechanisms and models of cancer stem cell multidrug resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.