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Article

The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity.

Alzheimer disease and associated disorders - 1 Jan 2000

West Nancy A, Tingle Jonathan V, Simino Jeannette, Selvin Elizabeth, Bressler Jan, Mosley Thomas H

Abstract excerpt

Previous reports suggest race/ethnic and sex heterogeneity in the association between the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma (PPARG) gene and cognitive decline. Tests of verbal memory, processing speed, and verbal fluency and a composite global Z-score were used to assess cognitive performance longitudinally in a large (n=11,620) biracial cohort of older adults in the...

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Identifiers

PMID: 29116943
DOI: 10.1097/WAD.0000000000000217
PMCID: PMC5938164

Genes

PPARG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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