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Article

The PPAR-gamma Pro12Ala polymorphism and risk of cognitive impairment in a longitudinal study.

Neurobiology of aging - 1 May 2010

West Nancy A, Haan Mary N, Morgenstern Hal

Abstract excerpt

The Pro12Ala polymorphism in the PPAR-gamma gene has been associated with reduced incidence of type 2 diabetes. Although diabetes has been implicated as a risk factor for dementia, the association of Pro12Ala with cognitive impairment is unclear. Dementia and cognitive impairment without dementia (CIND) were determined during six annual follow-up evaluations in a cohort of 929 older Latinos. Among those with...

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Identifiers

PMID: 18639367
DOI: 10.1016/j.neurobiolaging.2008.06.005
PMCID: PMC3099450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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