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Article

PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes.

Neuroscience letters - 21 Mar 2008

Johnson Wendy, Harris Sarah E, Starr John M, Whalley Lawrence J, Deary Ian J

Abstract excerpt

The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPARG; NCBI dbSNP rs1801282) has been associated with preservation of cognitive function, decreased risk of diabetes, and increased risk of obesity. We attempted to replicate these associations, testing cognitive function and lifetime cognitive change in 519 participants who took the same cognitive test at ages 11 and 79 years. Scores...

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Source

Identifiers

PMID: 18280041
DOI: 10.1016/j.neulet.2008.01.027

Genes

PPARG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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