Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study.

Neurology - 1 Jan 2013

Bressler Jan, Fornage Myriam, Demerath Ellen W, Knopman David S, Monda Keri L, North Kari E, Penman Alan, Mosley Thomas H, Boerwinkle Eric

Abstract excerpt

OBJECTIVE: To determine whether 4 genetic variants in the fat mass and obesity associated gene (FTO) identified in genome-wide association studies of diabetes and obesity are associated with cognitive change in midlife in the Atherosclerosis Risk in Communities (ARIC) Study. METHODS: ARIC is a prospective cohort study of the development of atherosclerosis in 15,792 individuals aged 45 to 64 years at baseline from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Cognition Disorders

Share to Genome-Wide Association Study

Share to Neuropsychological Tests

Share to Proteins

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 23136261
DOI: 10.1212/WNL.0b013e3182768910
PMCID: PMC3589198

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study.PMID 23136261Read ↗

Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study.Semantic proximity Read ↗

Reduced memory in fat mass and obesity-associated allele carriers among older adults with cardiovascular disease.Semantic proximity Read ↗

Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study.Semantic proximity Read ↗

Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study.Semantic proximity Read ↗

FTO genotype and aging: pleiotropic longitudinal effects on adiposity, brain function, impulsivity and diet.Semantic proximity Read ↗

Associations between obesity indices and cognitive function: Evidence from a middle-aged observational and Mendelian randomisation study.Semantic proximity Read ↗

Gene-environment interaction of body mass index and apolipoprotein E ε4 allele on cognitive decline.Semantic proximity Read ↗

Phenotypic heterogeneity of obesity-related brain vulnerability: one-size interventions will not fit all.Semantic proximity Read ↗

Association of metabolic obesity phenotypes with cognitive decline in the ELSA-Brasil study.Semantic proximity Read ↗

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly.Semantic proximity Read ↗

Subclinical atherosclerosis and subsequent cognitive function.Semantic proximity Read ↗

Vitamin D Receptor and Megalin Gene Polymorphisms Are Associated with Longitudinal Cognitive Change among African-American Urban Adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.