Article
The shifted balance between circulating follicular regulatory T cells and follicular helper T cells in patients with ulcerative colitis.
Clinical science (London, England : 1979) - 15 Dec 2017
Wang Xinrui, Zhu Yonggang, Zhang Manli, Hou Jie, Wang Hongjuan, Jiang Yanfang, Wang Haifeng, Gao Pujun
Abstract excerpt
B-cell immunity participates in the pathogenesis of ulcerative colitis (UC). The immune balance between follicular regulatory T (TFR) cells and follicular helper T (TFH) cells is important in regulating B-cell responses. However, the alteration of TFR/TFH balance in UC remains unclear. Peripheral blood from 25 UC patients and 15 healthy controls was examined for the frequencies of circulating TFR, TFH, and...
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