Article
Distinct phenotypic subpopulations of circulating CD4+CXCR5+ follicular helper T cells in children with active IgA vasculitis.
BMC immunology - 21 Oct 2016
Liu Deying, Liu Jinxiang, Wang Jinghua, Liu Congcong, Yang Sirui, Jiang Yanfang
Abstract excerpt
BACKGROUND: Circulating follicular helper T (Tfh) cells are a heterogeneous population of CD4+ helper T cells that promotes pathogenic immune responses in autoimmune diseases. In this study, we examined the status of different subpopulations of Tfh cells in peripheral circulation and their associations with various clinical characteristics of IgA vasculitis (IgAV). METHODS: According to the phenotypic expressions...
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