Article
Sources of spontaneous mutagenesis in bacteria.
Critical reviews in biochemistry and molecular biology - 1 Feb 2018
Schroeder Jeremy W, Yeesin Ponlkrit, Simmons Lyle A, Wang Jue D
Abstract excerpt
Mutations in an organism's genome can arise spontaneously, that is, in the absence of exogenous stress and prior to selection. Mutations are often neutral or deleterious to individual fitness but can also provide genetic diversity driving evolution. Mutagenesis in bacteria contributes to the already serious and growing problem of antibiotic resistance. However, the negative impacts of spontaneous mutagenesis on...
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