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Article

Correcting the Standard Errors of 2-Stage Residual Inclusion Estimators for Mendelian Randomization Studies.

American journal of epidemiology - 1 Nov 2017

Palmer Tom M, Holmes Michael V, Keating Brendan J, Sheehan Nuala A

Abstract excerpt

Mendelian randomization studies use genotypes as instrumental variables to test for and estimate the causal effects of modifiable risk factors on outcomes. Two-stage residual inclusion (TSRI) estimators have been used when researchers are willing to make parametric assumptions. However, researchers are currently reporting uncorrected or heteroscedasticity-robust standard errors for these estimates. We compared...

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Identifiers

PMID: 29106476
DOI: 10.1093/aje/kwx175
PMCID: PMC5860380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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